Bioavailability and Bioequivalance
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- Module
8-Bioavailability - Introduction to pharmacokinetics
- IV administration
- Oral administration
- Steady state concept
- Drug elimination
- Drug pharmacokinetics in renal dysfunction
- Multiple compartment pharmacokinetics
- Nonlinear pharmacokinetics
- Intermittent IV infusions
- Physiological approach to the clearance concept
- Kinetics of the pharmacological effects
- Therapeutic drug monitoring
- Introduction
- Introduction and definitions
- The first-pass effect
- Pharmacokinetic basis of bioequivalence
- Calculation of AUC (trapezoidal rule)
- Significance of the bioavailability and bioequivalence
- Design and evaluation of bioequivalence studies
- Summary
- Plot
- Questions