The pharmacokinetic principles have many applications in biomedical sciences:
- Pharmacological testing:
The pharmacokinetic principles are used to assess the relationship between the drug concentration and pharmacological effects. This is important to determine how much and how often the drug should be administered.
The pharmacokinetic ptinciples are used to assess tissue accumulation of drugs and how it is related to drug toxicity.
- Evaluation of organ function:
The pharmacokinetic principles are used to evaluate the function of eliminating organs. For example inulin is eliminated entirely by the kidney and the rate of inulin elimination can be used to assess the kidney function.
The pharmacokinetic ptinciples are used to design the dosing regimen (dose and dosing interval of a specific drug product) that can achieve the maximum therapeutic effect with minimum toxicity.
