Pharmacokinetic simulations involve graphical presentation of the drug profile (concentration) in the body given specific values for the pharmacokinetic parameters.
The plasma conc-time profile after a single oral dose administration can be described by the following equation:
The plasma conc-time profile can be simulated by choosing values for each of the parameters and then calculating the plasma conc at different time points.
| D =1000mg |
ka = 0.5hr-1 |
| F = 1 |
k = 0.15hr-1 |
| Vd = 50L |
This is the plasma conc-timeprofile given the specifiedparameter values
