Help:

This is an exercise to simulate how the change in the bioavailability affects the drug concentration-time profile in the body.

You are asked to select values for the bioavailability and then click plot to simulate the plasma concentration-time profile after single oral drug administration, assuming that the dose is 1000 mg, CLT is 6 L/hr, Vd is 30 L, and the absorption rate constant is 0.9 hr -1

Adjust the values for the X and Y axes to see the entire plot by clicking the adjust x scale or adjust y scale buttons.