Objectives

After completing this module you should be able to:

• Describe the plasma concentration-time profile after a single iv administration.

• Identify the factors that affect the plasma concentration-time profile after a single iv drug administration.

• Determine the pharmacokinetic parameters after a single iv drug administration.

• Analyze the effect of changing one or more of the pharmacokinetic parameters on the plasma concentration-time profile after a single iv drug administration.

• Utilize the mathematical expressions to calculate the plasma concentration at any time after a single iv drug administration.

• Calculate the appropriate iv dose required to achieve a specific drug concentration.