Help:

This exercise is designed to select the pharmacokinetic parameters that will achieve plasma drug concentration-time profile within the therapeutic range.

You are asked initially to select the minimum effective concentration and the minimum toxic concentration (The therapeutic range). Then you can select a value for each of the pharmacokinetic parameters and click plot to simulate the drug concentration-time profile after multiple oral drug administration.

Evaluate the achieved drug profile and how close it is to the therapeutic range of the drug.

Adjust the values for the X and Y axes to see the entire plot by clicking the adjust x scale or adjust y scale buttons.