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- Module
4-Half Life - Introduction to pharmacokinetics
- IV administration
- Oral administration
- Steady state concept
- Drug elimination
- Drug pharmacokinetics in renal dysfunction
- Multiple compartment pharmacokinetics
- Nonlinear pharmacokinetics
- Intermittent IV infusions
- Physiological approach to the clearance concept
- Kinetics of the pharmacological effects
- Therapeutic drug monitoring
- Objective
- Introduction
- Introduction
- Definition of the half life
- The relationship between the half life and the elimination rate constant
- Determination of the half life
- The mathematical expression that describes the drug conc-time profile
- Effect of half-line on the plasma drug concentration-time profile
- Summary
- Plot
- Questions