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- Module
13-Renal Excretion of drugs - Introduction to pharmacokinetics
- IV administration
- Oral administration
- Steady state concept
- Drug elimination
- Drug pharmacokinetics in renal dysfunction
- Multiple compartment pharmacokinetics
- Nonlinear pharmacokinetics
- Intermittent IV infusions
- Physiological approach to the clearance concept
- Kinetics of the pharmacological effects
- Therapeutic drug monitoring
- Objective
- Introduction
- Introduction
- Factors affecting the drug/metabolite profiles after a single iv drug administration ( Dose, CLT, Vd, fm, CLT(m), Vd(m) )
- Drug and metabolite conc-time profile during multiple drug administration
- Factors affecting the drug/metabolite conc-time profiles during multiple drug administration ( Dose, CLT, Vd, fm, Vd(m))
- Metabolite bioavailability, metabolite profile after extravascular drug administration, sequential metabolism
- Summary
- Plot
- Questions