Objectives

After completing this module you should be able to

• Define the steady state during multiple drug administration.

• Identify the factors that affect the steady state plasma concentration during multiple drug administration.

• Determine the steady state drug concentrations and patients pharmacokinetic parameters during multiple drug administration.

• Analyze the effect of changing one or more of the pharmacokinetic parameters on the steady state plasma concentration during multiple drug administration.

• Recommend the dosing regimen to achieve specific plasma concentrations in patients.

• Evaluate the appropriateness of certain dosing regimens for patients.