Examine the plasma conc-time profiles after administration of different doses.
Similar rate of decline
Similar slope at 10 mg/L
The initial drug plasma conc is :
The initial drug conc will be different after administration of different doses. This means that the plasma conc-time profiles will be different after administration of different doses since the rate of drug metabolism is dependent on the drug conc.
Notice that at any given drug conc, the rate of drug elimination (the of the curve) is similar regardless of the dose of the drug.
