Help:

This exercise is designed to simulate how the change in each of the pharmacokinetic parameters affects the plasma concentration-time profile during multiple oral administration of drugs that are eliminated by a single saturable elimination pathway, i.e. following nonlinear pharmacokinetics.

You are asked to select a value for each of the pharmacokinetic parameters and then click plot to simulate the drug concentration-time profile during multiple oral administration.

Adjust the values for the X and Y axes to see the entire plot by clicking the adjust x scale or adjust y scale buttons.