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- Module
17- Multiple Compartment Models (I) - Introduction to pharmacokinetics
- IV administration
- Oral administration
- Steady state concept
- Drug elimination
- Drug pharmacokinetics in renal dysfunction
- Multiple compartment pharmacokinetics
- Nonlinear pharmacokinetics
- Intermittent IV infusions
- Physiological approach to the clearance concept
- Kinetics of the pharmacological effects
- Therapeutic drug monitoring
- Objective
- Introduction
- Introduction
- One-compartment model versus two-compartment model
- The two-compartment pharmacokinetic model
- Plasma concentration-time profile in the two-compartment model
- Determination of the pharmacokinetic parameters
- Factors affecting the plasma concentration-time profile
- Summary
- Plot
- Questions