Steady State During Constant Rate IV Infusion

Drug administration by constant rate iv infusion will achieve a steady state as long as the rate of drug administration is constant and the drug elimination pathways follow first-order kinetics.

During constant drug administration.

IV infusion

Amount of drug in the body

Drug
Elimination

Steady State

At steady state the amount of the drug in the body will be constant, i.e.

The rate of drug administration = The rate of drug elimination

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