Factors Affecting the Steady State Drug Conc during Constant Rate IV Infusion

a- Infusion rate

Examine the steady state drug conc achieved during the administration of iv infusions at different rates, while keeping all other parameters constant.

Parameters
K0 (mg/hr) CLΤ(L/hr) Vd (L)
25 3.6 30
Inf.Rate (mg/hr)

The steady state plasma concentration is proportional to the infusion rate.

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