Concentration-time profile

The plasma concentration-time profile after an iv dose can be described by the following expression:

Cp2= Cp1 e-kt

c- If you know the elimination rate constant and the drug concentration at one time point, you can determine the time required for the drug concentration to decrease to a certain concentration.

You can substitute for the
values of Cp1, Cp2 and k in the
equation that describes
the plasma concentration time profile
to calculate time (t)
Cp1
Cp2
t = ?

d- If you know elimination rate constant and the drug concentration at one time point, you can estimate the drug concentration at any time prior to that time.

You can substitute for the of Cp2,
k, and t in the equation that describes
the plasma concentration-time
profile to calculate Cp1.
Cp1
Cp2
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