Dose : The administered dose, mg

F : The drug bioavailability, no units

Dosing interval : The time between doses, hours

ka : The first order absorption rate constant, hour-1

Vd : The vloume of distribution, liters

k : The first order elimination rate constant, hour-1

Dose : The administered dose, mg

F : The drug bioavailability, no units

Dosing interval : The time between doses, hours

ka : The first order absorption rate constant, hour-1

Vd : The vloume of distribution, liters

k : The first order elimination rate constant, hour-1

Select values for the different PK parameters by dragging the slider for each parameter to the right. The current parameter values will be displayed.

The drug and metabolite concentration-time profiles will be graphed when you click plot.

You can change the x and y scale values by clicking the Adjust scale buttons

Enter the maximum value for the X axis. The minimum value for the X axis will be zero.

Enter the maximum value for the Y axis. The minimum value for the Y axis will be zero.