Examine the conc-time profiles after administration of different doses, while keeping all other parameters constant.
|
D (mg) |
F |
CLΤ(L/hr) |
Vd (L) |
ka (hr-1) |
1000 |
1 |
7.5 |
50 |
0.5 |
Higher doses produce proportional increase in the AUC without affecting CLT, Vd, and k (first-order elimination).