The semilog graph paper allows plotting the data at logarithmic intervals without doing the actual logarithmic transformation of the numbers.
In order to determine the slope of a line drawn on a semilog graph paper it is necessary to do logarithmic transformation for the y values. The slope of the line in this case will be determined from the following relationship:
log y2 - log y1
X2- X 1The first-order absorption rate constant is the rate constant that determines the rate of drug absorption from the site of administration. Larger absorption rate constant results in faster rate of drug absorption.
The absorption rate constant determined after drug administration is an operative rate constant that accounts for all the necessary steps required for drug absorption into the systemic circulation including disintegration, dissolution and absorption.
The first-order absorption rate constant has units of time-1.