Drug absorption after oral administration

The amount of drug in the GIT Ai after oral administration declines at a rate dependent on the absorption rate constant, if the absorption process follows first-order kinetics.

A i = Dose -k a t

The rate of change of the amount of the drug in the body (A) depends on the rate of drug absorption and the rate of drug elimination.

dA

dt
= k a A i - k A
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