Module
9-Absorption Rate Constant
Introduction to pharmacokinetics
IV administration
Elimination Rate Constant
Volume of Distribution
Half Life
Total Body Clearance
Area Under The Curve
IV Drug Administration
Oral administration
Bioavailability and bioequivalence
Absorption rate constant
Oral drug administration
Steady state concept
Constant rate infusion
Multiple Drug Administration
Drug elimination
Renal Excretion of Drugs
Metabolite kinetics (I)
Metabolite kinetics (II)
Drug pharmacokinetics in renal dysfunction
Multiple compartment pharmacokinetics
Two compartment pharmacokinetic model (I)
Two compartment pharmacokinetic model (II)
Nonlinear pharmacokinetics
Intermittent IV infusions
Physiological approach to the clearance concept
Kinetics of the pharmacological effects
Therapeutic drug monitoring
Objectives
Introduction
Introduction
Drug absorption after oral administration
Determination of the pharmacokinetic parameters after a single oral dose
Determination of k
a
(the method of residuals)
Lag time
Flip flop of k
a
and k
Determination of k
a
(Wagner-Nelson method)
Summary
Plot
Plot
Linear
Semilog
Help
Questions
×
Module
9-Absorption Rate Constant
Introduction to pharmacokinetics
IV administration
Elimination Rate Constant
Volume of Distribution
Half Life
Total Body Clearance
Area Under The Curve
IV Drug Administration
Oral administration
Bioavailability and bioequivalence
Absorption rate constant
Oral drug administration
Steady state concept
Constant rate infusion
Multiple Drug Administration
Drug elimination
Renal Excretion of Drugs
Metabolite kinetics (I)
Metabolite kinetics (II)
Drug pharmacokinetics in renal dysfunction
Multiple compartment pharmacokinetics
Two compartment pharmacokinetic model (I)
Two compartment pharmacokinetic model (II)
Nonlinear pharmacokinetics
Intermittent IV infusions
Physiological approach to the clearance concept
Kinetics of the pharmacological effects
Therapeutic drug monitoring
Objective
Introduction
Introduction
Drug absorption after oral administration
Determination of the pharmacokinetic parameters after a single oral dose
Determination of k
a
(the method of residuals)
Lag time
Flip flop of k
a
and k
Determination of k
a
(Wagner-Nelson method)
Summary
Plot
Plot
Linear
Semilog
Help
Questions
The main mechanisms for drug transport across biological membranes include:
1 -
Passive diffusion
2 -
Active transport
3 -
Facilitated diffusion
4 -
All of the above