Dose : The administered dose, mg
F : The drug bioavailability, no units
ka : The first order absorption rate constant, hour -1
Vd : The volume of distribution, liters
k = (CLT/Vd) : The first order elimination rate constant, hour -1
Assume that the drug is administered as a single oral dose. All parameters will be kept constant, and only the absorption rate constant can be changed. Choose different values for the absorption rate constant and simulate the corresponding drug concentration-time profiles.
