Area Under The Curve
AUC
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- Module
6-Area Under The Curve - Introduction to pharmacokinetics
- IV administration
- Oral administration
- Steady state concept
- Drug elimination
- Drug pharmacokinetics in renal dysfunction
- Multiple compartment pharmacokinetics
- Nonlinear pharmacokinetics
- Intermittent IV infusions
- Physiological approach to the clearance concept
- Kinetics of the pharmacological effects
- Therapeutic drug monitoring
- Objective
- Introduction
- Introduction
- Mathematical description of the AUC
- The effect of dose on AUC
- Effect of total body clearance on the AUC
- Determination of the AUC
- The trapezoidal rule
- Summary
- Plot
- Questions