Objectives

After completing this module you should be able to:

• Define the area under the curve mathematically.

• Calculate the area under the curve after a single iv bolus dose.

• Describe how the change in the total body clearance affects the area under the curve after a single iv bolus dose.

• Describe how the change in the dose affects the area under the curve after a single iv bolus dose.

• Calculate the area under the curve using the trapezoidal rule.