Questions

After administration of a single iv bolus dose of 100 mg lidocaine, the plasma conc-time profile can be describe by the following expression: Cp= 2.6 e^-(5.0 t) + 0.52 e^-(0.4 t) , where t is in hours and Cp is in mg/L. What is lidocaine AUC after administration of this dose ?

1 - 32 mg-hr/L 2 - 1.82 mg-hr/L 3 - 0.52 mg-hr/L 4 - 1.3 mg-hr/L